Having worked in television, movies, as well as stage, Saundra has just finished a 10 month run on Broadway in the Tony award winning revival of NINE, starring Antonio Bandaras. She made her Broadway debut in Arthur Miller's A View From The Bridge starring opposite Tony LoBianco. She also starred in the Broadway musical version of Gabriel Garcia Marquez's Chronicle Of A Death Fortold, directed by Graciela Daniele, who also directed her in SMILE and the Off-Broadway musical hit Hello Again at Lincoln Center.

She's created roles in such Off-Broadway plays as Bedfellows at the Flea Theatre, young girl and the monsoon at Playwrights Horizons, Bandito at the Mark Taper Forum, Once Removed at the Long Wharf Theatre, Spike Heels at Second Stage and starred as "Eva Peron" in the National Tour of Evita.

On the big screen, she was last seen in Spike Lee's 25th Hour, and in the indie, Garmento. She's also played in High Life directed by Roger Hedden, Nick and Jane directed by Robert Morrow, Carlito's Way directed by Brian DePalma, Beat Street produced by Harry Belafonte, and The Pope Of Greenwich Village directed by Stuart Rosenberg.

On television, she was last seen and guest starred in the 14th season of Law And Order. She has the recurring role of "Jean Cusamano" and twin sister "Joan" on the hit HBO series The Sopranos. She also played series regular "Detective Gina Calabrese" on the ground breaking show Miami Vice for five years. She's guest starred on TV shows and movies of the week such as To Sir With Love Pt. II, NY Undercover, Edna Buchanan, Bill Cosby Mystery Movie, With Hostile Intent, Law And Order, Summer Stories and Mother Country.

On Daytime, Saundra created the role of "Carmen Santos" on CBS's longest running soap opera, Guiding Light. For her role, Santiago was the 2002 recipient of an Alma Award for Outstanding Actress in a Daytime Drama and a nominee in the same category in 2001. She is also a member of the famed Actors Studio.

Santiago holds a Bachelor of Fine Arts from the University of Miami and a Master of Fine Arts from Southern Methodist University. She was born in the Bronx and performs her cabaret act on occasion at such nightclubs as Danny's Skylight Room and the Triad in Manhattan.
Santiago repeated her primetime role on "Miami Vice" (1984) for one episode of "Days of Our Lives" (1965) in 1985 when the latter show went on location in Miami.