Nancy McKeon was born in Westbury, New York to Don and Barbara McKeon, began modeling baby clothes for the Sears catalogue at the age of two and she and her brother did over sixty-five commercials in seven years. She appeared briefly on the soap operas "The Secret Storm", and "Another World". When her brother, Philip McKeon won a role on the TV series, "Alice", the family moved to Los Angeles.

Her first real acting break came when she did the short-lived TV series "Stone" and guested on "Starsky and Hutch". The producers of "The Facts of Life" were so impressed by Nancy's performance as the street-wise girl in a pilot called "Dusty", they decided to sign her to play Jo on "The Facts of Life". Nancy has starred in the television movies, "High School U.S.A.", "Poison Ivy", "This Child Is Mine" and "The Greater Alarm". She provided the voices for animated shows like "Puppy's Great Adventure".



Was cast as the lead in the TV show "Working Girl" (1990), but left before production started. She was replaced by Sandra Bullock. Sister of Philip McKeon. Practiced a form of martial arts. Gave birth to her first child, daughter Aurora, on March 6, 2004. Was number 81 on vh1's "100 Greatest Kid Stars" (2005)