Delta Burke is best known for her portrayal as Suzanne Sugarbaker in CBS' Designing Women, which ran for five seasons and for which she received two Emmy nominations for Best Actress in a Comedy Series. When a teenager she represented Florida in the Miss America Pageant, and won a talent scholarship, which she used to attend a two-year study program at the London Academy of Music and Dramatic Arts.

She got her first television role within a month of her arrival in Los Angeles. She starred in the TV movie The Seekers and the series The Chisholms. She had the leading role in Filthy Rich and a starring role in HBO's first weekly series, 1st & Ten: The Championship.

Through her own production company, Perseverance, Inc., Delta produced and starred in the ABC television series Delta. She actually sang in the series and dyed her dark hair blonde for the role. She was reunited with Designing Women creator Linda Bloodworth-Thomason when she starred in and produced Women of the House, in which she reprised her role as Suzanne Sugarbaker.

Much of Delta's time now is spent designing clothing and managing her New York company, Delta Burke Design, which is becoming very successful. She is married to actor Gerald McRaney. They live in New Orleans when not working or traveling.