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An alumna of the Second City and Annoyance Theatre in Chicago, Illinois. Runs a cupcake and cheeseball business out of her Greenwich Village apartment when she is not acting. Occasionally works as a waitress at Mary's Fish Camp in the West Village. Wrote the play, "The Book of Liz", with her brother David Sedaris. She uses the money she gets for appearing on Late Show with David Letterman to buy a new pair of shoes for her next appearance. Amy keeps a free-roaming mini-rex rabbit named Dusty, whom she adopted from a rabbit rescue. Dusty's "bunny condo" was designed by her friend, designer Todd Oldham. Amy named her baked goods business after her first rabbit, Tattletail, a Netherlandish dwarf. ("Tattletail Industries" has since become "Amy's Cupcakes".) She is active in a NYC rabbit rescue and shelter, and is an honorary educator of the House Rabbit Society. Failed first grade. Idolized her brother David Sedaris when she was a child. Of all her relatives, she was closest to her father. Enjoys playing characters who "like themselves". Is of Greek descent. Collects decorative cupcake picks. She is best known for her grotesque yet strangely endearing character "Jerri" from Strangers with Candy. Raised Greek Orthodox.