According to Lucy O'Brien's new book, "Madonna: Like an Icon," out Tuesday, it almost happened.

O'Brien says Madonna, in her mid-30s, "desperately wanted children and had various relationships with unlikely men." The singer's friend Alison Clarkson recalls when she was briefly dating Tupac Shakur, one year before his death.

"She was going out with him ... but homegirls were saying to him, 'I can't believe you're going out with a white girl,'" - so she got dumped!

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