Jay Mohr, born in Verona, New Jersey, USA, wanted to be a comedian all of his life. He performed stand-up comedy at colleges, comedy clubs, and such television forums as An Evening at the Improv and Two Drink Minimum. He first gained national attention while a castmember on SNL 25, and became known for his impersonations of such people as Sean Penn and Christopher Walken.

He is a frequent guest on the New York City drive-time radio show "Opie & Anthony", where he adds his own commentary on the bizarre in-studio happenings and of course throws in the occasional Christopher Walken impersonation. Did a killer impersonation of Christopher Walken in a skit titled "Christopher Walken's Psychic Hotline" on SNL 25. Has a tattoo on the inside of his bicep which is dated with the word "Will". This is in respect of his cousin Will who was killed by a drunk driver His ex-wife, Nicole Chamberlain, is a former model who has developed a one-woman show, "Next!", about her experiences, particularly dealing with the audition process. Jay Mohr is a frequent contributor to "The Jungle" a radio show hosted by Jim Rome. Jay's razor sharp takes and opinions have earned him the nickname "Slam Man" on the show. [August 2001] He hosts a sports variety show in the vein of Frank Skinner & David Baddiel's Fantasy Football League, Mohr Sports, which debuted on ESPN in April 2002. He offers his unique and humorous insights on the world of sports in front of a live studio audience. The 30-minute weekly show features a timely, sports-themed comedy monologue, followed by interviews with athletes and entertainment personalities, remote segments and musical performances. Called SNL 25 "a constant struggle to get on camera". Has a son together with wife Nicole Chamberlain. Born on the same day as River Phoenix. Suffers from stage fright Engaged to Nikki Cox [February 3, 2006].