Dale Midkiff attended Salisbury University in Salisbury, Maryland, before moving to New York to work as a waiter while pursuing his acting career. His breakthrough role was when he landed the role of Elvis in the made-for-TV movie Elvis and Me. He later starred in Pet Sematary with Fred Gwynne and Love Potion No. 9 with Sandra Bullock.
He has three children: Cole, Eliza Rose and Ava Marie. He is the second of 8 children: six brothers and one sister. His parents are Jean and Thomas Midkiff. Has a nephew called Alex.